Lamentations 3:41

³⁹ Wherefore doth a living man complain, a man for the punishment of his sins?

⁴⁰ Let us search and try our ways, and turn again to the LORD.

Let us lift up our heart with our hands unto God in the heavens.

⁴² We have transgressed and have rebelled: thou hast not pardoned.

⁴³ Thou hast covered with anger, and persecuted us: thou hast slain, thou hast not pitied.

Do read the surrounding verses too, because the context often says more than a single verse.

Compare

Psalms 25:1
Unto thee, O LORD, do I lift up my soul.
Read in context
Psalms 28:2
Hear the voice of my supplications, when I cry unto thee, when I lift up my hands toward thy holy oracle.
Read in context
Psalms 86:4
Rejoice the soul of thy servant: for unto thee, O Lord, do I lift up my soul.
Read in context
Psalms 143:6–8
I stretch forth my hands unto thee: my soul thirsteth after thee, as a thirsty land. Selah.
Read in context
1 Thessalonians 2:8
So being affectionately desirous of you, we were willing to have imparted unto you, not the gospel of God only, but also our own souls, because ye were dear unto us.
Read in context
Psalms 63:4
Thus will I bless thee while I live: I will lift up my hands in thy name.
Read in context
Psalms 141:2
Let my prayer be set forth before thee as incense; and the lifting up of my hands as the evening sacrifice.
Read in context